Endocrine Abstracts

Chronic heart failure (CHF) is associated with maladaptive and prolonged neurohormonal and pro-inflammatory cytokine activation causing a metabolic shift favouring catabolism, vasodilator incapacity, and loss of skeletal muscle bulk and function. In men, androgens are important determinants of anabolic function and physical strength and also possess anti-inflammatory and vasodilatory properties. We conducted a randomised, double blind, placebo controlled trial of testosterone ...